Table 2.

Psychopathology and impaired neuropsychological performance. Due to logistical problems, the following data were not collected: Judgment of Line Orientation (5 non-NPSLE and 2 NPSLE), Complex Figure – copy (2 non-NPSLE) and 30-min recall (3 non-NPSLE), Sentence Repetition (1 non-NPSLE), Semantic Fluency (1 control and 3 non-NPSLE), Trail-making Test – Part A and Part B (1 non-NPSLE).

Controls, n = 85 %SLE Total, n = 85 %Non-NPSLE n = 57 %NPSLE n = 28 %Group Comparisons*, p
Psychopathology
  Hospital Anxiety and Depression Scale
    Anxiety ≥ 1121.235.335.135.7a
    Depression ≥ 114.720.014.032.1a, c, d
Neuropsychological tests
  Attentive Matrices5.916.512.325.0a, c
  Digit Span4.78.27.010.7
  Corsi-Block Tapping Test7.115.31417.9
  Judgment of Line Orientation4.710.37.715.4
  Complex Figure
    Copy4.73.51.87.1
    30-min recall4.710.67.017.9c
  Auditory Verbal Learning Test
    Immediate recall4.716.510.528.6a, c
    30-min recall4.72012.335.7a, c, d
    30-min recognition4.721.28.846.4a, c, d
  Sentence Repetition4.717.914.325.0a, c
  Semantic Fluency4.712.911.117.9c
  Letter-Word Fluency4.75.91.814.3d
Wisconsin Card Sorting Test
    No. categories4.79.410.57.1
    No. perseverative errors5.94.73.57.1
  Trail Making Test
    Part A4.711.93.628.6c, d
    Part B8.29.55.417.9
  Nine-Hole Peg Test5.916.55.339.3a, c, d
  Brief-Smell Identification Test4.711.85.325.0c, d
  • * Chi-square test or Fisher’s exact test (when applicable) were used for group comparisons;

  • a: controls vs SLE;

  • b: controls vs non-NPSLE;

  • c: controls vs NPSLE;

  • d: non-NPSLE vs NPSLE; such marked groups represent p < 0.05. SLE: systemic lupus erythematosus.