Osteoarthritis Research Society International (OARSI) Simplified Response in intention-to-treat (ITT) population and patients with baseline Western Ontario and McMaster Universities Osteoarthritis Index pain subscale scores > 10 and > 13 for the double-blind study.
| OARSI Simplified Response | Response | Civamide Cream 0.075% (%) | Civamide Cream 0.01% (control) (%) | Treatment Effect | p |
|---|---|---|---|---|---|
| ITT Population | Yes | 68 | 58 | 10% | 0.006 |
| No | 32 | 42 | |||
| Baseline pain > 10 | Yes | 68 | 54 | 14% | 0.002 |
| No | 32 | 46 | |||
| Baseline pain > 13 | Yes | 78 | 51 | 27% | < 0.001 |
| No | 22 | 49 |