Comparison of serum cytokines and IL-8 levels among groups. Values are expressed as mean ± SD.
| Cytokine | AS, n = 11 | AS with Anti-TNF-α, n = 5 | Controls, n = 8 | p* |
|---|---|---|---|---|
| IL-6, pg/ml | 535.2 ± 84.2 | 4.4 ± 0.6 | 2.5 ± 0.2 | < 0.0001 |
| IL-8, pg/ml | 1114.1 ± 425.9 | 6.1 ± 1.2 | 2.3 ± 0.2 | 0.03 |
| IL-12, pg/ml | 10.3 ± 1.8 | 3 ± 0.2 | 3.2 ± 0.1 | 0.001 |
| IL-17A, pg/ml | 25 ± 3.2 | 2.1 ± 0.5 | 3.3 ± 0.2 | < 0.0001 |
| IFN-γ, pg/ml | 96.1 ± 16 | 20.2 ± 3.1 | 42.1 ± 2.3 | 0.001 |
| TNF-α, pg/ml | 126.3 ± 7.6 | 4.7 ± 0.8 | 6 ± 0.4 | < 0.0001 |
↵* One-way ANOVA. AS: ankylosing spondylitis; TNF: tumor necrosis factor; IFN: interferon.