Laboratory findings in patients with Sjögren’s syndrome, with and without p19 or tax antibody in the salivary glands.
| p19 | tax | p19 or tax | ||||
|---|---|---|---|---|---|---|
| Characteristic | Positive, n = 10 | Negative, n = 23 | Positive, n = 10 | Negative, n = 23 | Positive, n = 14 | Negative, n = 19 |
| Antinuclear antibody titer | 164.0 ± 125.7 | 243.5 ± 121.8 | 220.0 ± 135.0 | 219.1 ± 125.8 | 191.4 ± 127.6 | 240.0 ± 125.1 |
| High anti-Ro titer, > 200 U/ml (%) | 4/10 (40)* | 18/23 (78.3) | 6/10 (60) | 16/23 (69.6) | 8/14 (57.1) | 14/19 (73.7) |
| Anti-La titer, U/ml | 33.1 ± 61.6 | 44.9 ± 63.6 | 56.7 ± 77.7 | 34.0 ± 55.1 | 41.7 ± 69.3 | 40.2 ± 58.8 |
| Rheumatoid factor titer, IU/ml | 14.8 ± 10.9* | 54.6 ± 86.0 | 19.1 ± 20.1* | 51.3 ± 84.5 | 18.1 ± 17.4* | 58.7 ± 91.5 |
| C3, mg/dl | 87.6 ± 23.3* | 108.7 ± 22.3 | 94.5 ± 15.3 | 105.7 ± 27.0 | 89.1 ± 21.6** | 112.0 ± 21.9 |
| C4, mg/dl | 18.6 ± 6.2 | 21.6 ± 7.3 | 19.8 ± 6.1 | 21.1 ± 7.5 | 18.6 ± 6.2 | 22.3 ± 7.3 |
| IgG, mg/dl | 1409.9 ± 902.1 | 1952.8 ± 1304.8 | 1549.0 ± 1000.0 | 1892.3 ± 1297.0 | 1472.2 ± 965.2 | 2021.2 ± 1339.4 |
| IgA, mg/dl | 336.6 ± 191.9 | 303.2 ± 117.0 | 369.1 ± 181.5 | 289.0 ± 116.4 | 328.9 ± 168.8 | 302.2 ± 121.6 |
| IgM, mg/dl | 112.3 ± 43.2 | 167.9 ± 79.9 | 146.3 ± 70.5 | 152.8 ± 78.0 | 138.9 ± 64.1 | 159.5 ± 82.3 |
| White blood cells, /mm3 | 5510.0 ± 1969.5 | 5356.5 ± 2179.8 | 5130.0 ± 1566.3 | 5522.0 ± 2300.0 | 5421.4 ± 1763.8 | 5389.5 ± 2347.1 |
| Hemoglobin, g/dl | 12.6 ± 1.9 | 12.7 ± 0.8 | 12.4 ± 1.3 | 12.8 ± 1.2 | 12.7 ± 1.6 | 12.7 ± 0.9 |
| Platelets, × 103/μl | 228.3 ± 81.1 | 344.6 ± 528.0 | 477.4 ± 799.2 | 236.3 ± 77.8 | 404.7 ± 676.2 | 239.1 ± 82.2 |
| Lymphocytes, /μl | 2364.0 ± 948.0*** | 1228.2 ± 523.0 | 2014.0 ± 1165.3 | 1380.4 ± 605.9 | 2002.9 ± 1027.8* | 1255.3 ± 519.5 |