Clinical data and dermal endothelial staining results in patients with SLE compared to controls.
| Patients | Controls | |
|---|---|---|
| Demographic, laboratory, clinical characteristics | ||
| No. | 27 | 5 |
| Age, yrs | 34 | 37 |
| White, % | 26 | 40 |
| Female, % | 89 | 80 |
| Complements, % abnormal | 73 | 0 |
| dsDNA, % abnormal | 77 | 0 |
| GFR, ml/min | 84 | 98 |
| GFR < 60, % | 27 | 0 |
| Nephrotic, % | 37 | 0 |
| Skin biopsy characteristics† | ||
| mEPCR, % | 94* | 59 |
| ICAM-1, % | 81** | 67 |
| Adiponectin, % | 45 | 43 |
| CD31, % | 98 | 92 |
↵† Continuous variables, median values, positive (≥ 2+; 0–3 range).
↵* p = 0.046, patients versus controls;
↵** p = 0.037, patients versus controls. GFR: glomerular filtration rate; mEPCR: membrane endothelial protein C receptor; ICAM-1: intercellular adhesion molecule-1; SLE: systemic lupus erythematosus.