Comparison of extrarenal involvement and systemic symptoms at diagnosis. Data are n (%) unless otherwise specified.
| PTU-induced AAV, n = 36 | Primary AAV, n = 174 | p | |
|---|---|---|---|
| Lung and lower airway | 10 (27.8) | 118 (67.8) | < 0.01 |
| Cutaneous | 6 (16.7) | 20 (11.5) | NS |
| Ear-nose-throat | 13 (36.1) | 54 (31.0) | NS |
| Gastrointestinal tract | 0 | 13 (7.5) | NS |
| Nervous system | 0 | 31 (17.8) | < 0.01 |
| Cardiovascular | 0 | 5 (2.9) | NS |
| General | |||
| Fever | 16 (44.4) | 81 (46.6) | NS |
| Weight loss | 3 (8.3) | 34 (19.5) | NS |
| BVAS, median (range) | 13.5 (6–34) | 21.0 (4–39) | < 0.01 |
PTU: propylthiouracil; AAV: ANCA-associated vasculitis; BVAS: Birmingham Vasculitis Assessment Score; NS: nonsignificant; ANCA: antineutrophil cytoplasmic antibody.