Peripheral blood/serum/plasma | | | | |
Bone alkaline phosphatase | | | | ✓ |
C-reactive protein | ✓ | ✓ | ✓ | ✓ |
Cartilage oligomeric matrix protein | ✓ | ✓ | | |
Ratio of C-propeptide of type II collagen to collagen fragment neoepitopes Col2–3/4 (long mono) | ✓ | | | |
Interleukin 6 (IL-6) | ✓ | ✓ | | |
Matrix metalloproteinase-3 | ✓ | ✓ | ✓ | |
Melanoma inhibitory activity | | ✓ | | |
Macrophage-colony stimulating factor | | | | ✓ |
Osteoprotegerin | ✓ | | | |
Circulating osteoclast precursors | | | | ✓ |
Receptor activator of nuclear factor kappa-B ligand | | | | ✓ |
Synovial fluid | | | | |
Chemokine (C-C motif) ligand 3 | | ✓ | ✓ | |
IL-1 | | ✓ | ✓ | |
IL-1 receptor antagonist | | ✓ | ✓ | |
IL-6 | | ✓ | ✓ | |
IL-8 | | ✓ | ✓ | |
Synovial tissue | | | | |
CD3-positive cells | | | ✓ | |
Skin | | | | |
IL-17 pathway genes | | | ✓ | |