Cox proportional hazards model survival analysis.
| Statistical Method | Sample Size | Bayesian Hazard Ratio*, median (95% CrI) |
|---|---|---|
| SScPAH | ||
| Unmatched data | 275 | 1.50 (1.02, 2.19) |
| Matched data, noninformative prior | 98 | 1.09 (0.59, 2.02) |
| Matched data, informative optimistic prior | 98 | 1.06 (0.70, 1.63) |
| Matched data, informative optimistic prior | 98 | 0.94 (0.65, 1.46) |
| IPAH | ||
| Unmatched data | 155 | 1.31 (0.63, 2.92) |
| Matched data, noninformative prior | 66 | 1.01 (0.35, 3.01) |
| Matched data, informative group prior | 66 | 1.07 (0.57, 1.98) |
| Matched data, informative optimistic prior | 66 | 0.94 (0.54, 1.64) |
↵* Hazard ratio > 1 indicates increased mortality associated with warfarin exposure. Hazard ratio < 1 indicates decreased mortality associated with warfarin exposure. CrI: credible interval; SScPAH: scleroderma-associated pulmonary arterial hypertension; IPAH: idiopathic PAH.