Demographic and clinical characteristics of patients with RS3PE or pure PMR.
| Characteristic, n = 151 | RS3PE, n = 28 | Pure PMR, n = 123 | p |
|---|---|---|---|
| Mean age, yrs | 75.0 | 74.2 | 0.669 |
| Disease duration until diagnosis, mo | 2.2 | 2.6 | 0.722 |
| Length of followup, mean, mo | 30.0 | 37.1 | 0.267 |
| Male, n (%) | 22 (78.6) | 51 (41.4) | 0.001 |
| Smoking, n (%) | 11 (39.3) | 19 (15.5) | 0.008 |
| Diabetes, n (%) | 47 (25.0) | 22 (17.9) | 0.427 |
| Hypertension, n (%) | 13 (46.4) | 42 (34.2) | 0.277 |
| Hyperlipidemia, n (%) | 5 (17.9) | 22 (17.9) | 1.000 |
| Pain and AM stiffness in the following regions, n (%) | |||
| Shoulder | 25 (89.3) | 110 (89.4) | 1.000 |
| Hip/thigh | 11 (39.3) | 91 (74.0) | 0.001 |
| Neck/torso | 12 (42.9) | 56 (45.5) | 0.836 |
| Systemic signs and symptoms*, n (%) | 18 (64.3) | 57 (46.3) | 0.098 |
| Fever ≥ 38°C | 10 (35.7) | 24 (19.5) | 0.080 |
| Malaise or fatigue | 5 (17.9) | 31 (25.4) | 0.471 |
| Depression | 3 (10.7) | 2 (1.6) | 0.044 |
| Weight loss | 8 (28.6) | 20 (16.3) | 0.175 |
| Anorexia | 3 (10.7) | 12 (9.8) | 1.000 |
| ESR ≥ 40 mm/h, n (%) | 23 (82.1) | 110 (89.4) | 0.331 |
| ESR, mm/h† | 79.6 ± 33.2 | 84.4 ± 32.7 | 0.486 |
| Hemoglobin, g/dl† | 11.1 ± 1.5 | 11.5 ± 1.6 | 0.263 |
| CRP†, mg/dl, normal range 0.01–0.4 | 7.1 ± 4.9 | 8.4 ± 7.2 | 0.387 |
| IgM-RF | |||
| Tested | 28 | 115 | |
| Positive results, n (%) | 0 (0.0) | 19 (16.5) | |
| ACPA | |||
| Tested | 17 | 33 | |
| Positive result | 0 | 0 | |
↵* Systemic symptoms and signs were considered positive if 1 of the conditions on the list was present.
↵† Values represent mean ± SD. ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; RS3PE: remitting seronegative symmetrical synovitis with pitting edema; PMR: polymyalgia rheumatica; RF: rheumatoid factor; ACPA: anticitrullinated protein antibodies.