Table 2.

ISN/RPS classification of 195 patients with SLE and comparison between patients with and without clinical renal involvement. Data are number (%) unless otherwise indicated.

Total, n = 195Overt Subset, n = 109Silent Subset, n = 86p
ISN/RPS classification
  Nil15 (8)4 (4)11 (13)
  Class I28 (14)3 (3)25 (29)
  Class II44 (23)16 (15)28 (33)
  Class III36 (19)28 (26)8 (9)
    III, n23167
    III + V, n13121
  Class IV47 (24)42 (39)5 (6)
    IV, n34313
    IV + V, n13112
  Class V25 (13)16 (15)9 (10)
  Class VI0 (0)0 (0)0 (0)
Immune depositsn = 169n = 103n = 66
  IgG131 (78)88 (85)43 (65)0.002
  IgM137 (81)88 (85)49 (74)0.07
  IgA122 (72)84 (82)38 (58)0.0007
  C3144 (85)88 (85)46 (70)0.014
  C1q144 (85)92 (89)52 (79)0.06
  • P values were estimated by the chi-square test to allow comparisons between patients with and without renal involvement. ISN/RPS: International Society of Nephrology/Renal Pathology Society; SLE: systemic lupus erythematosus; overt subset: patients with clinical renal involvement; silent subset: patients without clinical renal involvement.