Characteristics of studies on the MBL2 gene and RA.
| Population | Alleles/genotypes Studied | Clinical Features |
|---|---|---|
| Danish7 | AA, AO, and OO | Joint destruction |
| White Danish8 | AA, AO, and OO | Early erosive arthritis |
| Finnish9 | AA, AO, and OO | Systemic amyloidosis |
| Danish10,11 | AA, AO, and OO | Atherosclerosis and cardiovascular disease |
| Southern Chinese12 | Allele B | Associated with RA |
| Japanese13 | Allele B | Associated with autoimmune disorders |
| Dutch14 | AA, AO, and OO | Not associated with RA |
| Indian Whites15 | Allele B | Protection against RA |
MBL: mannose-binding lectin; RA: rheumatoid arthritis.