Age- and sex-adjusted risk of mortality in patients with RA according to baseline PCS, MCS, and HAQ. N = 10,319 patients, 1317 deaths, and 64,888 patient-years of observation.
| Variable | Category | % in Category | HR (95% CI) | p |
|---|---|---|---|---|
| PCS | ≥ 50 | 14.5 | 1.0 (referent) | |
| 41–50 | 22.6 | 1.6 (1.2, 2.1) | < 0.001 | |
| 31–40 | 30.6 | 2.0 (1.6, 2.6) | < 0.001 | |
| 21–30 | 27.3 | 3.1 (2.5, 4.0) | < 0.001 | |
| ≤ 20 | 5.1 | 4.9 (3.6, 6.4) | < 0.001 | |
| MCS | ≥ 50 | 57.2 | 1.0 (referent) | |
| 41–50 | 21.4 | 1.4 (1.2, 1.6) | < 0.001 | |
| 31–40 | 15.2 | 1.7 (1.5, 2.0) | < 0.001 | |
| 21–30 | 5.5 | 2.0 (1.5, 2.5) | < 0.001 | |
| ≤ 20 | 0.7 | 1.6 (0.6, 3.8) | 0.304 | |
| HAQ | 0.00 | 12.3 | 1.0 (referent) | |
| 0.125–0.375 | 14.8 | 1.4 (1.1, 1.8) | 0.010 | |
| 0.500–0.875 | 25.7 | 1.5 (1.2, 1.9) | 0.002 | |
| 1.000–1.375 | 22.3 | 1.8 (1.4, 2.2) | < 0.001 | |
| 1.500–1.875 | 17.2 | 2.7 (2.2, 3.5) | < 0.001 | |
| 2.000–2.375 | 6.4 | 4.0 (3.1, 5.2) | < 0.001 | |
| 2.500–3.000 | 1.3 | 5.5 (3.9, 7.7) | < 0.001 |
PCS: SF-36 physical component summary score; MCS: SF-36 mental component summary score; HAQ: Health Assessment Questionnaire-Disability Index; RA: rheumatoid arthritis.