Table 4.

Comparison of clinical characteristics between ISN/RPS class III or IV and others (Nil, class I, II, V) among patients with clinical renal involvement. Except for the percentages, data represent the median value and range.

CharacteristicsClass II, IVNil, Class I, II, Vp
Enrolled patients, n7039
Age at renal biopsy, yrs34 (15–64)31 (17–68)0.44
Women, n (%)64 (91)36 (92)0.87
Disease duration, yrs2 (0–23)1 (0–14)0.20
Patients who received PSL, n (%)55 (79)14 (36)< 0.0001
Dosage of PSL, mg/day10 (0–80)10 (0–70)0.52
Patients who received IA, n (%)11 (16)5 (13)0.68
Proteinuria, mg/day1464 (0–2900)689 (0–7995)0.001
Presence of active urinary sediments, n (%)47 (67)20 (51)0.15
Serum creatinine, mg/dl0.9 (0.4–4.0)0.7 (0.5–1.3)0.002
eGFR, ml/min/1.73 m261 (12–151)85 (35–136)0.002
Anti-dsDNA, IU/ml67 (0–9635)17 (0–354)0.001
Anti-SM positivity, n (%)9 (13)7 (18)0.47
CH50, U/ml15.8 (0–50.7)25.3 (0–46.3)0.091
C3, mg/dl44 (10–136)54 (19–150)0.08
C4, mg/dl9 (1–52)13 (2–31)0.32
  • P values were estimated to allow comparisons between ISN/RPS class III or IV and others. ISN/RPS: International Society of Nephrology/Renal Pathology Society; PSL: prednisolone; IA: immunosuppressive agents; eGFR: estimated glomerular filtration rate.