Table 5.

Comparison of clinical features between ISN/RPS class III or IV and others (Nil, class I, II, V) among patients without clinical renal involvement. Except for percentages, data represent the median value and range.

CharacteristicsClass III, IVNil, Class I, II, Vp
Enrolled patients, n1373
Age at renal biopsy, yrs27 (22–56)29 (11–69)0.80
Women, n (%)13 (100)68 (93)1
Disease duration, yrs5 (0–9)0 (0–19)0.018
Patients received PSL, n (%)9 (69)40 (55)0.38
Dosage of PSL, mg/day10 (0–30)5 (0–60)0.35
Patients who received IA, n (%)1 (8)3 (4)0.49
Proteinuria, mg/day108 (0–300)0 (0–350)0.45
Serum creatinine, mg/dl0.7 (0.5–0.8)0.6 (0.3–1.0)0.54
eGFR, ml/min/1.73 m283 (73–133)91 (68–206)0.34
Anti-dsDNA, IU/ml97 (4–2180)35 (0–1280)0.03
Anti-Sm positivity, n (%)2 (15)9 (12)0.76
CH50, U/ml14.5 (0–46.6)25.5 (0–49.8)0.02
C3, mg/dl40 (22–99)59 (21–129)0.007
C4, mg/dl10 (2–19)13 (1–40)0.08
  • P values were estimated to allow comparisons between ISN/RPS class III or IV and others. ISN/RPS: International Society of Nephrology/Renal Pathology Society; PSL: prednisolone; IA: immunosuppressive agents; eGFR: estimated glomerular filtration rate.