Genotype and allele frequencies of UTS2 gene Thr21 Met (T21M) polymorphism in cases of diffuse or limited cutaneous systemic sclerosis and controls. Data are number (%).
| Genotypes/Alleles | Controls, n = 205 | Cases with dcSSc, n = 99 | p | Cases with lcSSc, n = 90 | p |
|---|---|---|---|---|---|
| T/T | 20 (9.8) | 21 (21.2) | 29 (32.2) | ||
| T/M | 90 (43.9) | 40 (40.4) | 0.0243 | 29 (32.2) | < 0.0001 |
| M/M | 95 (46.3) | 38 (38.4) | 0.0134 | 32 (35.6) | < 0.0001 |
| T | 130 (31.7) | 82 (41.4) | 87 (48.3) | ||
| M | 280 (68.3) | 116 (58.6) | 0.0236 | 93 (51.7) | 0.0002 |
lcSSc: limited cutaneous systemic sclerosis; dsSSc: diffuse cutaneous SSc.