Comparison between 15 cases in our study and 42 other cases in the literature.
| Characteristics | Our Study | Literature Cases | p |
|---|---|---|---|
| Women:men | 13:2 | 33:9 | 0.709 |
| Age, yrs | 28.9 ± 9.9 | 34.2 ± 14.4 | 0.189 |
| SLE-associated HPS | 11/15 | 37*/42 | 0.223 |
| Infection-associated HPS | 3/15 | 5†/42 | 0.422 |
| Use of steroids | 15/15 | 42/42 | 1.000 |
| Steroid pulse therapy | 7/15 | 33/42 | 0.045 |
| Use of immunosuppressive agents | 8/15 | 15/42 | 0.358 |
| Use of IVIG | 7/15 | 9/42 | 0.113 |
| Died | 1/15 | 3/42 | 1.000 |
↵* These 37 include patients with HPS whose triggering factors were both SLE and infection as well as only SLE.
↵† Five include patients with HPS whose triggering factors were both SLE and infection as well as only infection. SLE: systemic lupus erythematosus; HPS: hemophagocytic syndrome; IVIG: intravenous immunoglobulin.