Table 1.

UBE2L3 rs5754217 genotype and allele frequencies in controls and cases stratified by anti-La autoantibody status.

BackgroundClinical CategoryNGGGTTTMAF (T)La+ Cases vs La– Cases, AdditiveLa+ Cases vs LA– Cases, RecessiveLa+ Cases vs Controls, AdditiveLa+ Cases vs Controls, Recessive
African AmericanControls23974127380.425OR 1.57, p = 0.050OR 2.21, p = 0.027OR 1.69, p = 0.022OR 2.55, p = 0.0061
Cases25271129520.462
La+ Cases461021150.554
La– Cases20661108370.442
European AmericanControls105643650.219OR 1.32, p = 0.47OR 3.52, p = 0.27OR 1.31, p = 0.46OR 1.66, p = 0.38
Cases143885140.206
La+ Cases137510.269
La– Cases130814630.200
  • La+ indicates patients with a positive test for anti-La antibodies. La– indicates patients who lack anti-La antibodies. MAF: minor allele frequency.