Table 2.

Allelic and genotype association analysis of single-nucleotide polymorphism (SNP) in the LRP5 gene in case control.

		Allele						Genotype
		Freq (case)	Freq (control)					Case Frequency			Control Frequency
SNP	Allele	Freq (case)	Freq (control)	p	OR	P_c	95% CI	1/1	1/2	2/2	1/1	1/2	2/2	Fisher’s p	P_c
LRP5SNP1	G	0.052	0.059	0.627	0.866	0.92	0.647–2.059	0.897	0.103	—	0.882	0.118	—	0.616	0.94
rs312016	G	0.377	0.406	0.399	0.888	0.86	0.854–1.485	0.372	0.502	0.126	0.335	0.518	0.146	0.681	0.96
rs312015	G	0.385	0.382	0.936	1.011	0.92	0.752–1.300	0.370	0.490	0.140	0.376	0.482	0.141	0.986	1.00
rs312024	G	0.422	0.447	0.450	0.902	0.92	0.848–1.450	0.330	0.497	0.173	0.288	0.529	0.182	0.644	0.95
rs41494349	G	0.090	0.082	0.689	1.102	0.92	0.584–1.502	0.823	0.173	0.003	0.841	0.153	0.006	0.787	0.97
rs638051	G	0.336	0.300	0.256	1.181	0.82	0.835–1.328	0.408	0.512	0.080	0.476	0.447	0.076	0.346	0.87
rs4930573	C	0.177	0.195	0.494	0.888	0.97	0.631–1.249	0.030	0.294	0.676	0.041	0.308	0.651	0.753	0.97
rs686921	C	0.254	0.256	0.954	0.991	1.00	0.743–1.369	0.545	0.401	0.054	0.571	0.347	0.082	0.305	0.89
rs471966	G	0.273	0.262	0.719	1.057	0.95	0.700–1.279	0.528	0.398	0.074	0.547	0.382	0.071	0.927	1.00
rs531163	G	0.271	0.268	0.914	1.017	1.00	0.728–1.328	0.528	0.401	0.070	0.535	0.394	0.071	0.988	1.00
LRP5SNP2	A	0.085	0.097	0.534	0.864	0.92	0.546–1.368	0.007	0.157	0.837	0.000	0.194	0.806	0.341	0.90
LRP5SNP3	A	0.219	0.131	0.0018	1.859	0.0087	1.255–2.755	0.121	0.195	0.684	0.034	0.195	0.772	0.0098	0.0316

P_c: p value after multiple testing correction.