Table 2.

Allelic and genotype association analysis of single-nucleotide polymorphism (SNP) in the LRP5 gene in case control.

AlleleGenotype
Freq (case)Freq (control)Case FrequencyControl Frequency
SNPAllelepORPc95% CI1/11/22/21/11/22/2Fisher’s pPc
LRP5SNP1G0.0520.0590.6270.8660.920.647–2.0590.8970.1030.8820.1180.6160.94
rs312016G0.3770.4060.3990.8880.860.854–1.4850.3720.5020.1260.3350.5180.1460.6810.96
rs312015G0.3850.3820.9361.0110.920.752–1.3000.3700.4900.1400.3760.4820.1410.9861.00
rs312024G0.4220.4470.4500.9020.920.848–1.4500.3300.4970.1730.2880.5290.1820.6440.95
rs41494349G0.0900.0820.6891.1020.920.584–1.5020.8230.1730.0030.8410.1530.0060.7870.97
rs638051G0.3360.3000.2561.1810.820.835–1.3280.4080.5120.0800.4760.4470.0760.3460.87
rs4930573C0.1770.1950.4940.8880.970.631–1.2490.0300.2940.6760.0410.3080.6510.7530.97
rs686921C0.2540.2560.9540.9911.000.743–1.3690.5450.4010.0540.5710.3470.0820.3050.89
rs471966G0.2730.2620.7191.0570.950.700–1.2790.5280.3980.0740.5470.3820.0710.9271.00
rs531163G0.2710.2680.9141.0171.000.728–1.3280.5280.4010.0700.5350.3940.0710.9881.00
LRP5SNP2A0.0850.0970.5340.8640.920.546–1.3680.0070.1570.8370.0000.1940.8060.3410.90
LRP5SNP3A0.2190.1310.00181.8590.00871.255–2.7550.1210.1950.6840.0340.1950.7720.00980.0316
  • Pc: p value after multiple testing correction.