Ratios of observed to expected events (O:E ratios) for all ischemic heart disease (IHD) diagnoses combined according to age at first renal biopsy, age at IHD event, time from first renal biopsy (latency), calendar-year period of first renal biopsy, and renal status, respectively, in a cohort of 104 patients diagnosed with lupus nephritis between 1971 and 1995 and followed throughout 2006.
| Feature | Observed* | O:E Ratio (95% CI) |
|---|---|---|
| Age at first renal biopsy, yrs | ||
| < 31 | 13 | 17.1 (9.1–29) |
| ≥ 31 | 18 | 4.8 (2.8–7.5) |
| Age at IHD event, yrs | ||
| < 30 | 0 | 0.0 (0.0–142) |
| 30–39 | 11 | 42.3 (21–76) |
| 40–49 | 8 | 8.5 (3.6–17) |
| 50–59 | 7 | 6.0 (2.4–12) |
| 60+ | 5 | 2.3 (0.8–5.5) |
| Latency, yrs | ||
| 0–4 | 7 | 7.4 (3.0–15) |
| 5–9 | 10 | 9.5 (4.5–17) |
| 10–14 | 7 | 6.2 (2.5–13) |
| 15+ | 7 | 5.0 (2.0–10) |
| Calendar-year period of first renal biopsy | ||
| 1971–79 | 3 | 4.7 (0.9–14) |
| 1980–89 | 16 | 5.7 (3.3–9.3) |
| 1990–95 | 12 | 10.8 (5.6–19) |
| Renal status | ||
| – ESRD | 24 | 5.8 (3.7–8.6) |
| + ESRD | 7 | 19.4 (7.8–40) |
↵* Observed number of first-time hospital discharge diagnoses. ESRD: Endstage renal disease (as defined in text).