Demographic, clinical, and hemodynamic characteristics. All data are expressed as mean ± SD unless otherwise specified.
| Characteristics | N = 50 |
|---|---|
| Age, yrs | 61 (11) |
| Sex, n (% women) | 49 (98) |
| Race, n (% white) | 45 (90) |
| NYHA FC, n (%) | |
| I: | 2 (4) |
| II: | 13 (26) |
| III: | 30 (60) |
| IV: | 5 (10) |
| Total lung capacity, n (% predicted) | 82 (18) |
| DLCO, n (% predicted) | 51 (18) |
| 6MWT, m | 325 (88) |
| Disease duration before index echocardiography, days | 1147 (829) |
| PAH-specific therapy at index echocardiography, n (%) | 25 (50) |
| Deaths, n (%) | 25 (50) |
| Heart rate, bpm | 82 (16) |
| Systolic blood pressure, mm Hg | 125 (21) |
| Diastolic blood pressure, mm Hg | 69 (13) |
| Systemic vascular resistance, dynes-s/cm5 | 4722 (1821) |
| Right atrial pressure, mm Hg | 9 (5) |
| Mean pulmonary artery pressure, mm Hg | 42 (10) |
| Cardiac index, l/min/m2 | 2.4 (0.8) |
| PCWP, mm Hg | 10 (3) |
| Pulmonary vascular resistance, Wood units | 9.2 (5.1) |
| Pulmonary artery saturation (%) | 64.8 (9.1) |
| Stroke volume index, ml/m2 | 32 (13) |
| RVSWI, g-m/m2 | 13.5 (5.9) |
| SV/PP, mm Hg/ml | 1.25 (0.73) |
NYHA FC: New York Heart Association functional class; PCWP: pulmonary capillary wedge pressure, RVSWI: right ventricular stroke work index; SV/PP: stroke volume/pulse pressure.