Summary of Patient Global Impression of Change at endpoint.
| Patient Status, n (%) | Placebo, n = 184 | Pregabalin 300 mg/day, n = 184 | Pregabalin 450 mg/day, n = 182 | Pregabalin 600 mg/day, n = 186 |
|---|---|---|---|---|
| No. assessed* | 169 | 164 | 165 | 155 |
| Any improvement | 95 (56.2) | 108 (65.9) | 121 (73.3) | 107 (69.0) |
| Very much improved | 7 (4.1) | 13 (7.9) | 16 (9.7) | 20 (12.9) |
| Much improved | 43 (25.4) | 45 (27.4) | 50 (30.3) | 46 (29.7) |
| Minimally improved | 45 (26.6) | 50 (30.5) | 55 (33.3) | 41 (26.5) |
| No change | 43 (25.4) | 28 (17.1) | 27 (16.4) | 25 (16.1) |
| Any worsening | 31 (18.3) | 28 (17.1) | 17 (10.3) | 23 (14.8) |
| Minimally worse | 11 (6.5) | 9 (5.5) | 7 (4.2) | 10 (6.5) |
| Much worse | 17 (10.1) | 14 (8.5) | 8 (4.8) | 10 (6.5) |
| Very much worse | 3 (1.8) | 5 (3.0) | 2 (1.2) | 3 (1.9) |
| Comparison of pregabalin treatment groups vs placebo | ||||
| p value** | NA | 0.0768 | 0.0017† | 0.0227† |