Table 1.

Baseline characteristics of the 69 patients with rheumatoid arthritis (RA).

Characteristics
Demographic
  Age, yrs, median (range)55 (21–75)
  Women, n (%)56 (81)
Disease status
  Disease duration, mo, median (range)48 (3–480)
  Rheumatoid factor-positive, n (%)55 (80)
  ACPA-positive, n (%)55 (80)
  DAS28, median (range)5.7 (3.2–7.7)
  Synovitis score*, median (range)4 (1–7)
Medications, n (%)
  Corticosteroids31 (45)
  Methotrexate16 (23)
  Leflunomide7 (10)
  Sulfasalazine3 (4)
  Hydroxychloroquine3 (4)
  • * Synovitis score according to Krenn, et al13,14, based on the following basic morphological measures of synovitis: intimal hyperplasia, inflammatory infiltration, and activation of resident cells/synovial stroma, including fibroblasts, endothelial cells, histiocytes, macrophages, and multinucleated giant cells. All measures are graded: 0 (absent), 1 (slight), 2 (moderate), or 3 (strongly positive). The values of all measures are summarized, resulting in a final score between 0 and 9. Median reference value for RA = 5.019. ACPA: anticitrullinated protein antibody; DAS28: 28-joint Disease Activity Score.