Univariate and multivariate Cox regression analyses of the predictors for all-cause mortality among dialysis patients with SLE. All p values are statistically significant (p < 0.05) except multivariate analysis of peripheral arterial disease.
| Variable | Univariate Analysis HR (95% CI) | Multivariate Analysis HR (95% CI) |
|---|---|---|
| Age at dialysis, yrs | ||
| < 45 (reference) | 1 | 1 |
| 45–64 | 2.581 (2.354–2.829) | 1.991 (1.813–2.185) |
| ≥ 65 | 5.749 (5.254–6.291) | 4.344 (3.960–4.765) |
| Sex, male vs female | 1.141 (1.102–1.195) | 1.228 (1.179–1.279) |
| First modality of dialysis, HD vs PD | 0.699 (0.637–0.767) | 1.142 (1.039–1.254) |
| Diabetes mellitus | 2.243 (2.151–2.339) | 1.881 (1.799–1.968) |
| Hypertension | 1.394 (1.322–1.469) | 0.937 (0.886–0.990) |
| Heart failure | 1.910 (1.824–2.000) | 1.390 (1.323–1.460) |
| Coronary artery disease | 1.889 (1.807–1.974) | 1.200 (1.144–1.258) |
| Cerebrovascular disease | 1.901 (1.800–2.007) | 1.377 (1.302–1.456) |
| Peripheral arterial disease | 1.458 (1.305–1.628) | 1.056 (0.945–1.181) |
| Malignancy | 1.730 (1.600–1.871) | 1.667 (1.540–1.804) |
HR: hazard ratio; SLE: systemic lupus erythematosus; HD: hemodialysis; PD: peritoneal dialysis.