Table 2.

Serial measurements of high resolution computed tomography (HRCT) scores, and measurements of skin thickening, peripheral vascular disease, and functional status in 7 patients who completed the entire study period. Results are shown as the mean ± SD.

FeaturePretreatment12 Months24 Monthsp
HRCT scores
  Ground-glass opacity5.4 ± 4.06.1 ± 3.95.7 ± 3.50.2
  Pulmonary fibrosis8.3 ± 2.49.3 ± 2.89.1 ± 2.20.052
  Honeycomb cysts2.1 ± 3.13.0 ± 3.14.5 ± 3.70.02
Modified Rodnan skin score13.9 ± 11.612.6 ± 9.812.7 ± 9.80.9
Oral aperture, mm40.9 ± 13.638.9 ± 12.143.1 ± 10.80.6
FTP, right, mm1.3 ± 1.31.5 ± 2.51.7 ± 1.90.5
Raynaud’s condition score2.6 ± 2.33.5 ± 2.83.3 ± 2.50.6
No. digital ulcers0.9 ± 2.30.0 ± 0.00.1 ± 0.40.4
SHAQ-DI0.7 ± 0.80.7 ± 0.90.8 ± 0.80.4
SHAQ-VAS1.3 ± 0.51.2 ± 0.81.4 ± 0.60.7
  • FTP: finger tip-to-palm distance; SHAQ: Scleroderma Health Assessment Questionnaire; DI: disability index; VAS: visual analog scale.