Table 3.

PBC screening antibodies and PBC in different SSc-related autoantibodies.

Total ACA, n = 67Anti-Topo I, n = 64Anti-RNAP III, n = 14Anti-Th/To, n = 8Other Autoantibodies, n = 48
PBC screen +, %32.8 (22/67)1,2,312.5 (8/64)17 (1/14)225 (2/8)314.5 (7/48)6
PBC, %8.9 (6/67)404004 (2/48)
PBC or elevated ALP, %16.4 (11/67)51.5 (1/64)50011.7 (4/34)
  • 1 p = 0.0068;

  • 2 p = 0.053;

  • 3 p = nonsignificant;

  • 4 p = 0.028;

  • 5 p = 0.0045;

  • 6 p = 0.036. PBC: primary biliary cirrhosis; ALP: alkaline phosphatase; ACA: anticentromere; anti-topo I: antitopoisomerase I: anti-RNAP III: anti-RNA polymerase III.