Minimally important differences for UCLA SCTC GIT 2.0 scales and total gastrointestinal tract score. A negative sign indicates improvement in the scale scores.
| UCLA SCTC GIT 2.0 | Overall GI Anchor | Upper GI Anchor | Lower GI Anchor | |||||
|---|---|---|---|---|---|---|---|---|
| Scale | Patient-rated* | Mean Change (95% CI) | Effect Size | Mean Change (95% CI) | Effect Size | Mean Change (95% CI) | Effect Size | Overall Mean Change† |
| Reflux | Much better (n = 11–12) | −0.35 (−0.69, 0) | −0.68 | −0.26 (−0.54, 0.02) | −0.52 | −0.3 | ||
| Somewhat better (n = 15–18) | −0.26 (0.44, −0.07) | −0.58 | −0.27 (−0.56, 0.03) | −0.58 | −0.26 | |||
| About the same (n = 66–71) | 0.02 (−0.06, 0.1) | 0.03 | −0.02 (−0.01, 0.05) | −0.04 | −0.001 | |||
| Somewhat worse (n = 15–19) | 0.15 (0, 0.29) | 0.29 | 0.22 (0.05, 0.39) | 0.32 | 0.19 | |||
| Much worse (n = 0–1) | NA | NA | 0.41 | −0.52 | NA | |||
| Distension/Bloating | Much better (n = 11–15) | −0.71 (−1.15, 0.27) | −0.74 | −0.41 (−0.74, 0.08) | −0.52 | −0.56 | ||
| Somewhat better (n = 15–18) | −0.04 (−0.44, 0.37) | −0.05 | −0.24 (−0.75, 0.26) | −0.34 | −0.14 | |||
| About the same (n = 66–71) | 0.11 (−0.05, 0.26) | 0.14 | 0.04 (−0.11, 0.2) | 0.06 | 0.08 | |||
| Somewhat worse (n = 13–19) | −0.03 (−0.29, 0.23) | −0.03 | 0.27 (0.05, 0.49) | 0.34 | 0.12 | |||
| Much worse (n = 0–1) | NA | 0 | NA | NA | ||||
| Diarrhea | Much better (n = 11–15) | −0.41 (−0.74, −0.08) | −0.61 | −0.43 (−0.76, −0.1) | −0.64 | −0.42 | ||
| Somewhat better (n = 16–18) | −0.22 (−0.72, 0.28) | −0.29 | −0.16(−0.7, 0.38) | −0.19 | −0.19 | |||
| About the same (n = 66–69) | −0.1 (−0.25, 0.05) | −0.16 | −0.03 (−0.16, 0.1) | −0.05 | −0.06 | |||
| Somewhat worse (n = 12–18) | 0.14 (−0.15, 0.43) | 0.21 | 0 (−0.56, 0.56) | 0 | 0.07 | |||
| Much worse (n = 0) | NA | NA | NA | |||||
| Constipation | Much better (n = 11–15) | −0.11 (−0.55, 0.32) | −0.22 | −0.11 (−0.43, 0.21) | −0.24 | −0.11 | ||
| Somewhat better (n = 16–18) | −0.15 (−0.47, 0.16) | −0.28 | −0.19 (−0.53, 0.15) | −0.34 | −0.17 | |||
| About the same (n = 66–69) | −0.01 (−0.11, 0.1) | −0.02 | −0.05 (−0.13, 0.03) | −0.11 | −0.03 | |||
| Somewhat worse (n = 13–19) | 0.03 (−0.14, 0.21) | 0.08 | 0.23 (−0.14, 0.6) | 0.37 | 0.13 | |||
| Much worse (n = 0) | 0.41 | NA | NA | NA | ||||
| Fecal soilage | Much better (n = 11–15) | −0.36 (−0.82, 0.09) | −0.56 | −0.2 (−0.57, 0.17) | −0.35 | −0.28 | ||
| Somewhat better (n = 15–17) | −0.18 (−0.55, 0.2) | −0.21 | −0.2 (−0.57, 0.17) | −0.21 | −0.19 | |||
| About the same (n = 64–67) | 0.06 (−0.06–0.19) | 0.11 | 0.01 (−0.1, 0.13) | 0.03 | 0.04 | |||
| Somewhat worse (n = 13–19) | 0.05 (−0.14, 0.25) | 0.07 | 0.08 (−0.09, 0.24) | 0.09 | 0.06 | |||
| Much worse (n = 0) | NA | NA | NA | NA | ||||
| Emotional well-being | Much better (n = 11–15) | −0.28 (−0.56, −0.01) | −0.53 | −0.3 (−0.57, 0.03) | −0.58 | −0.27 (−0.49, −0.06) | −0.56 | −0.29 |
| Somewhat better (n = 14–18) | −0.4 (−0.79, 0) | −0.57 | −0.26 (−0.64, 0.11) | −0.36 | −0.42 (−0.81, 0.02) | −0.58 | −0.36 | |
| About the same (n = 66–71) | 0 (−0.09, 0.08) | 0 | −0.05 (−0.16, 0.06) | −0.08 | 0 (−0.09, 0.1) | 0.01 | −0.02 | |
| Somewhat worse (n = 13–19) | 0.14 (−0.07, 0.35) | 0.23 | 0.15 (−0.1, 0.4) | 0.19 | 0.2 (−0.07, 0.46) | 0.24 | 0.16 | |
| Much worse (n = 0–1) | NA | 0.44 | NA | NA | NA | NA | ||
| Social functioning | Much better (n = 11–15) | −0.23 (−0.5, 0.05) | −0.54 | −0.27 (−0.55, 0) | −0.65 | −0.2 (−0.4, 0) | −0.52 | −0.23 |
| Somewhat better (n = 14–18) | −0.04 (−0.15, 0.08) | −0.1 | −0.11 (−0.22, 0) | −0.33 | −0.07 (−0.18, 0.03) | −0.24 | −0.07 | |
| About the same (n = 64–69) | 0.02 (−0.04, 0.07) | 0.04 | 0.03 (−0.04, 0.1) | 0.09 | 0.09 (0.01, 0.17) | 0.31 | 0.05 | |
| Somewhat worse (n = 13–19) | 0.24 (−0.1, 0.57) | 0.39 | 0.33 (−0.02, 0.68) | 0.43 | 0.08 (−0.33, 0.48) | 0.08 | 0.21 | |
| Much worse (n = 0–1) | NA | −0.17 | NA | NA | NA | NA | ||
| Total GIT score | Much better (n = 11–15) | −0.51 (−0.85, −0.16) | −0.86 | −0.36 (−0.56–0.17) | −0.82 | −0.33 (−0.48, −0.17) | −0.81 | −0.40 |
| Somewhat better (n = 15–18) | −0.18 (−0.32, −0.03) | −0.5 | −0.28 (−0.57, 0.01) | −0.56 | −0.16 (−0.32, 0.01) | −0.44 | −0.20 | |
| About the same (n = 66–71) | 0.02 (−0.04, 0.08) | 0.04 | 0 (−0.07, 0.07) | 0 | 0.01 (−0.07, 0.1) | 0.03 | 0.01 | |
| Somewhat worse (n = 13–19) | 0.12 (−0.03, 0.27) | 0.22 | 0.2 (0.99, 0.31) | 0.36 | 0.05 (−0.16, 0.25) | 0.07 | 0.12 | |
| Much worse (n = 0–1) | NA | NA | NA | |||||
↵* n represents patients who are categorized into 5 different responses. n are presented as a range because the number of patients in each category is different based on their responses to the anchors. For Reflux and Distension/Bloating scales, we used overall and upper GI anchor; for Diarrhea, Constipation, and Fecal soilage, we used overall and lower GI anchors.
↵† Overall mean change is the average of mean scores for different anchors. NA: not applicable.