Table 4.

Multivariate logistic regression analysis using good and/or moderate EULAR response as outcome at 3, 6, and 12 months.

Variable (at inclusion)	3 Months, N = 1301		6 Months, N = 1232		12 Months, N = 1271
Variable (at inclusion)	OR (95% CI)	p	OR (95% CI)	p	OR (95% CI)	p
Age (decades)	1.0 (0.92–1.09)	0.95	1.00 (0.91–1.09)	0.92	0.94 (0.87–1.02)	0.12
Female	0.78 (0.59–1.03)	0.07	0.75 (0.56–0.99)	0.04	0.51 (0.39–0.66)	0.0001
Previous smoker	0.76 (0.56–1.02)	0.07	0.73 (0.54–0.99)	0.04	0.96 (0.73–1.26)	0.75
Current smoker	0.56 (0.41–0.77)	0.0001	0.56 (0.41–0.77)	0.0001	0.69 (0.51–0.95)	0.02
RF	0.84 (0.65–1.09)	0.20	0.84 (0.65–1.10)	0.22	0.82 (0.65–1.05)	0.12
HAQ	0.76 (0.61–0.96)	0.02	0.77 (0.61–0.97)	0.02	0.85 (0.69–1.06)	0.15
DMARD treatment	1.83 (1.34–2.51)	0.0001	1.90 (1.37–2.63)	0.0001	1.46 (1.06–2.01)	0.02
Disease duration, mo	0.96 (0.92–1.00)	0.07	0.97 (0.93–1.02)	0.20	0.94 (0.90–0.98)	0.006
Glucocorticoid treatment	1.36 (1.03–1.78)	0.03	1.40 (1.07–1.85)	0.02	0.93 (0.72–0.19)	0.55
DAS28	1.56 (1.38–1.77)	0.0001	1.60 (1.41–1.83)	0.0001	0.82 (0.73–0.92)	0.001

RF: rheumatoid factor; HAQ: Health Assessment Questionnaire; DMARD: disease-modifying antirheumatic drug; DAS28: Disease Activity Score (28 joints).