Table 2.

Association of serum matrix Gla protein (MGP) concentration with radiographic hand osteoarthritis (OA).

Serum MGP Quartiles (* Adjusted Mean Serum MGP, ng/ml ± SE)Crude Prevalence† of Radiographic Hand OA (%)Adjusted OR*† (95% CI)
Lowest quartile
  129.8 ± 20.510.681.0 (ref)
Second quartile
  174.2 ± 11.815.661.40 (0.94–2.06)
Third quartile
  214.9 ± 10.013.601.21 (0.80–1.81)
Highest quartile
  281.0 ± 45.817.101.21 (0.79–1.85)

  • ↵* Adjusted for age, sex, body mass index, education, smoking status, physical activity, plasma phylloquinone, and 25-(OH) vitamin D.

  • ↵† The crude and adjusted OR for hand OA across quartiles of serum MGP concentration, among older men and women.