Age | Gender | Adverse Allopurinol Event | Febuxostat Starting Dose (mg) | Febuxostat Current Dose, mg | SUA Initial, mg/dl | SUA Post, mg/dl | Percentage SUA Reduction | Duration on Drug (mo) | Estimated Cr CI (ml/min) |
---|---|---|---|---|---|---|---|---|---|
85 | F | Exfoliative erythroderma requiring hospitalization | 40 | 0 | 10.9 | Unknown | xxx | 0.25 | 33.7 |
52 | F | Full body rash with desquamation | 40 | 80 | 14 | 9.5 | 32 | 15 | 60.0 |
74 | F | Dyspnea, likely acute renal failure | 40 | 40 | 11.3 | 6.9 | 39 | 12 | 56.2 |
83 | M | Full body rash | 40 | 80 | 9.8 | 4.7 | 52 | 13 | 52.3 |
66 | M | Rash | 40 | 60 | 10.2 | 4.6 | 55 | 12 | 65.1 |
70 | M | Acute renal failure, eosinophilia and vasculitis on bx | 20 | 20 | 11 | 5.9 | 46 | 7 | 27.4 |
71 | M | Desquamating skin rash | 40 | 40 | 9.9 | Unknown | xxx | 1.5 | 50.6 |
60 | M | Desquamating skin rash of mouth | 40 | 80 | 13.7 | 5.6 | 59 | 9 | 91.2 |
75 | F | Rash | 40 | 40 | 10.3 | 4.8 | 53 | 3 | 18.3 |
71 | M | Severe cutaneous reaction | 40 | 100 | 8.8 | 5 | 43 | 13 | 57.6 |
62 | M | Diffuse rash | 40 | 40 | 8.7 | 5.7 | 34 | 16 | 29.2 |
80 | F | Diffuse cutaneous reaction on worsening chronic kidney diagnosis | 40 | 40 | 10.2 | 4.9 | 52 | 13 | 14.7 |
75 | M | Rash and eosinophilia | 40 | 40 | 7.5 | 5.6 | 25 | 6 | 81.0 |
SUA: serum uric acid; eCLcr: estimated creatinine clearance.