Factors associated with preeclampsia and preterm delivery in women with SLE with and without lupus nephritis.
| Characteristics | Preeclampsia, OR (95% CI) | < 37 Weeks, OR (95% CI) | ||
|---|---|---|---|---|
| No Previous Lupus Nephritis, n = 64 | Previous Lupus Nephritis, n = 43 | No Previous Lupus Nephritis, n = 64 | Previous Lupus Nephritis, n = 43 | |
| Maternal age, yrs | ||||
| ≤ 35 | 1.00 | 1.00 | 1.00 | 1.00 |
| > 35 | 3.55 (0.87–14.13) | 2.08 (0.47–9.29) | 0.91 (0.17–5.02) | 1.78 (0.41–7.80) |
| BMI, kg/m2 | ||||
| ≤ 30 | 1.0 | * | * | * |
| > 30 | 10.70 (1.5–75.8) | |||
| Prepregnancy eGFR, ml/min/1.73m2 | ||||
| ≥ 90 | 1.00 | 1.00 | * | 1.00 |
| < 90 | 22.5 (1.86–271.95) | 12.00 (2.16–66.55) | 1.25 (0.27–5.77) | |
| Proteinuria at booking | ||||
| Trace or none | 1.00 | 1.00 | * | 1.00 |
| 1 + or more | 1.18 (0.12–11.42) | 5.7 (1.25–25.92) | 4.05 (0.99–16.57) | |
| Systolic BP, mmHg at booking | ||||
| ≤ 130 | 1.00 | 1.00 | 1.00 | 1.00 |
| > 130 | 2.12 (0.20–23.02) | 3.71 (0.83–16.55) | 2.94 (0.26–32.97) | 5.57 (1.22–25.36) |
| Diastolic BP, mmHg at booking | ||||
| ≤ 80 | 1.00 | 1.00 | 1.00 | 1.00 |
| > 80 | 7.29 (1.22–43.41) | 4.82 (1.02–22.84) | 4.33 (0.65–28.86) | 4.06 (0.88–19.86) |
↵* No women in one or more outcome category, therefore OR not calculated. SLE: systemic lupus erythematosus; BMI: body mass index; eGFR: estimated glomerular filtration rate; BP: blood pressure.