Table 6.

Renal outcome in women with SLE with and without lupus nephritis.

Clinical MeasuresNo Previous Lupus NephritisPrevious Lupus Nephritis (PN)
Prepregnancy creatinine, μmol/ln = 38n = 33
Median (IQR)63 (55–71)69* (62–94)
Prepregnancy eGFR, ml/min/1.73m2n = 38n = 33
Median (IQR)115 (100–125)99** (75–122)
Prepregnancy eGFR, ml/min/1.73m2n = 38n = 33
  < 905 (21%)12 (49%)***
  < 6004 (12%)
Postpartum creatinine, μmol/ln = 45n = 38
Median (IQR)62 (56–71)67† (58–94)
Postpartum eGFR, ml/min/1.73m2n = 45n = 38
Median (IQR)113 (102–124)105‡ (71–117)
Months followupn = 30n = 31
Median (IQR)39 (23–63)39 (19–64)
Fall in eGFRn = 13n = 17
Median (range)9 (3–38)11 (2–22)
Rate of fall in eGFR, ml/min/1.73m2/monthn = 13n = 17
Median (range)0.56 (0.06–5.40)0.29 (0.06–2.26)
Fall in eGFR, > 30 ml/min/1.73m2n = 30n = 31
No. (%)2 (6%)0 (0%)

  • ↵* p = 0.015,

  • ↵** p = 0.051,

  • ↵*** 0.022,

  • ↵† p = 0.038,

  • ↵‡ p = 0.01.

  • SLE: systemic lupus erythematosus; IQR: interquartile range; eGFR: estimated glomerular filtration rate.