Table 1.

Replication of association in RA samples from Colombia (cases = 353, controls = 368).

SNP	Cyto-position	Gene	Disease	Minor Allele	MAF Case	MAF Control	p	OR (95% CI)	Statistical Power^†
rs3890745	1p36	MMEL1	RA	C	0.466	0.464	0.959	1.00 (0.80–1.25)	0.42
rs3766379	1q23.3	CD244	RA	T	0.409	0.439	0.279	0.88 (0.70–1.10)	0.41
rs6682654	1q23.3	CD244	RA	G	0.439	0.474	0.247	0.86 (0.68–1.10)	0.42
rs4505848	4q27	KIAA1109	RA, CED, T1D	G	0.376	0.355	0.427	1.09 (0.87–1.38)	0.40
rs17388568	4q27	ADAD1	T1D	A	0.145	0.156	0.570	0.91 (0.68–1.23)	0.26
rs42041	7q21–q22	CDK6	RA	G	0.192	0.200	0.741	0.95 (0.72–1.26)	0.30
rs2736340	8p22–23	C8orf13-BLK	RA, SLE	T	0.468	0.349	0.0001	1.63 (1.27–2.10)	0.39
rs13277113	8p22–23	C8orf13-BLK	SLE	A	0.465	0.373	0.0009	1.46 (1.16–1.82)	0.40
rs881375	9q33	PHF19-TRAF1	RA, SLE	T	0.296	0.313	0.551	0.92 (0.70–1.20)	0.38
rs3761847	9q33	TRAF1-C5	RA, SLE	G	0.391	0.403	0.703	0.95 (0.74–1.22)	0.41
rs4750316	10p15.1	DKFZp667F0711	RA	C	0.120	0.145	0.198	0.80 (0.58–1.11)	0.25
rs1678542	12q13.13	KIF5A	RA	G	0.406	0.439	0.246	0.87 (0.69–1.09)	0.41
rs3184504	12q24	SH2B3	RA, CED	T	0.322	0.322	0.990	0.99 (0.77–1.29)	0.38
rs17696736	12q24.13	C12orf30	RA	G	0.301	0.299	0.932	1.01 (0.79–1.27)	0.37
rs12708716	16p13.13	CLEC16A	MS, T1D	G	0.288	0.316	0.263	0.87 (0.69–1.10)	0.38
rs1143679	16p11.2	ITGAM	SLE	A	0.121	0.107	0.450	1.14 (0.80–1.63)	0.20
rs763361	18q22.3	CD226	MS, T1D	T	0.440	0.393	0.122	1.21 (0.94–1.54)	0.41
rs4810485	20q12–q13	CD40	RA	T	0.203	0.206	0.882	0.97 (0.74–1.28)	0.31

↵† Statistical power calculated for α = 0.05, OR = 1.2, given sample size and control minor allele frequency for each SNP. RA: rheumatoid arthritis; SNP: single-nucleotide polymorphism; T1D: type 1 diabetes; SLE: systemic lupus erythematosus; CED: celiac disease; MS: multiple sclerosis; MAF: minor allele frequency.