JSN per joint space area in patients with RA as assessed by MRI† and radiography (Exercise 2, n = 14). All “Total” MRI JSN scores (MRITotal MRISvdHTotal and MRIGenant-Total) add the scores from MCP2-5 to the respective wrist scores.
| MRI (n = 294) | X-ray (n = 140) | JSN in Areas Assessed by X-ray (n = 140) | JSN in Areas Not Assessed by X-ray (n = 140) | Specific Wrist Joint Spaces Included in Simplified MRI Scores | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Presence (Score ≥ 1) | Score, Median (Range) | Presence (Score ≥ 1) | Score, Median (Range) | Both X-ray and MRI | Neither X-ray nor MRI | X-ray, Not MRI | MRI, Not X-ray | MRI, Not X-ray | SvdH | Genant | JSN14 | JSN7 | |
| MCP2 | 5 | 0 (0–3) | 2 | 0 (0–4) | 2 | 9 | 0 | 3 | |||||
| MCP3 | 5 | 0 (0–1) | 1 | 0 (0–2) | 1 | 9 | 0 | 4 | |||||
| MCP4 | 4 | 0 (0–2) | 1 | 0 (0–2) | 0 | 9 | 1 | 4 | |||||
| MCP5 | 4 | 0 (0–2) | 1 | 0 (0–2) | 1 | 10 | 0 | 3 | |||||
| CMC1 | 5 | 0 (0–2) | –* | –* | 5 | ||||||||
| CMC2 | 4 | 0 (0–4) | –* | –* | 4 | X | X | ||||||
| CMC3 | 11 | 1 (0–4) | 2 | 0 (0–4) | 2 | 3 | 0 | 9 | X | X1/3 | X | X | |
| CMC4 | 6 | 0 (0–3) | 1 | 0 (0–2) | 1 | 8 | 0 | 5 | X | X1/3 | X | ||
| CMC5 | 8 | 1 (0–3) | 1 | 0 (0–1) | 1 | 6 | 0 | 7 | X | X1/3 | X | ||
| Trm-Trd | 7 | 0.5 (0–4) | –* | –* | 7 | ||||||||
| Trd-Cap | 11 | 1 (0–4) | –* | –* | 11 | X | |||||||
| Cap-Ham | 8 | 1 (0–4) | –* | –* | 8 | X | |||||||
| Trm-Sca | 4 | 0 (0–4) | –** | –** | –** | –** | –** | –** | –** | X1/2 | X | ||
| Trd-Sca | 5 | 0 (0–4) | 3** | 0 (0–4)** | 3** | 9** | 0** | 2** | ** | X1/2 | X | X | |
| Cap-Sca | 3 | 0 (0–4) | 2 | 0 (0–4) | 2 | 11 | 0 | 1 | X | X1/2 | X | ||
| Cap-Lun | 2 | 0 (0–4) | –* | –* | 2 | X1/2 | X | X | |||||
| Ham-Tri | 4 | 0 (0–4) | –* | –* | 4 | X | X | ||||||
| Sca-Lun | 3 | 0 (0–4) | –* | –* | 3 | ||||||||
| Lun-Tri | 5 | 0 (0–4) | –* | –* | 5 | X | |||||||
| Rad-Sca | 3 | 0 (0–2) | 3 | 0 (0–3) | 2 | 10 | 1 | 1 | X | X1/2 | X | X | |
| Rad-Lun | 4 | 0 (0–2) | –* | –* | 4 | X1/2 | X | X | |||||
| Sum | 111 | – | 17 | – | 15 | 84 | 2 | 39*** | 53 | ||||
↵† MRI assessments by Reader 5 (experienced radiologist) are presented.
↵* Not assessed by radiography;
↵** Trm-Sca and Trd-Sca are analyzed as one area (as for the SvdH radiographic method).
↵*** Only 10 separate joint spaces were included because the SvdH radiographic method assesses JSN in Trm-Sca and Trd-Sca as one area; therefore “n” in column 2 (294) is 14 higher than the sum of “n” in columns 6–9. X: Included in score with the weight of 1; X1/2: Included in score with the weight of 1/2; X1/3: Included in score with the weight of 1/3, in agreement with procedure in SvdH and Sharp-Genant radiographic scoring systems. MCP: metacarpophalangeal, CMC: carpometacarpal, Trm: trapezium, Trd: trapezoid, Cap: capitate, Ham: hamate, Sca: scaphoid; Lun: lunatum; Tri: triquetrum, Rad: radius, Uln: ulna, JSN: joint space narrowing, SvdH: Sharp-van der Heijde.