Table 2.

Comparisons of immunosuppressive therapies. Treatment is defined as ever vs never exposure to the medications. Data are percentages of subjects taking each medication.

MedicationCTD-ILD n = 76IPF, n = 148pSSc-ILD, n = 26Non-SSC CTD-ILD, n = 50p
Methotrexate18.41.4< 0.00017.724.00.1200
Mycophenolate mofetil23.714.90.102711.530.00.0725
Prednisone57.948.70.189823.176.0< 0.0001
TNF inhibitor21.10< 0.0001032.00.0012
  • CTD-ILD: connective tissue disease-associated interstitial lung disease; IPF: idiopathic pulmonary fibrosis; SSc-ILD: systemic sclerosis-associated ILD; non-SSc CTD-ILD: nonsystemic sclerosis CTD-ILD; TNF: tumor necrosis factor.