Results of fixed-effects models to identify changes in disability over time in SSc. Unless indicated, results are standardized using the values obtained at baseline visits.
| Variable | HAQ Over Time: Standardized Fixed-effect Estimates | |
| Mixed Model | Selection Model ω = 0 | |
| Estimate (95% CI) | Estimate (95% CI) | |
| Age | 0.11 (0.03, 0.18) | 0.10 (0.02, 0.17) |
| Diffuse disease | 0.23 (0.16, 0.31) | 0.26 (0.19, 0.33) |
| Visit number | 0.031 (0.003, 0.060) | 0.056 (0.025, 0.087) |
| Unstandardized visit no. | 0.022 (0.002, 0.042) | 0.039 (0.018, 0.061) |
| Variable | HAQ-related Symptoms Over Time: Standardized Fixed-effect Estimates | |
| Mixed Model | Selection Model ω = 0 | |
| Estimate (95% CI) | Estimate (95% CI) | |
| Age | 0.12 (0.05, 0.18) | 0.11 (0.05, 0.17) |
| Diffuse disease | 0.23 (0.16, 0.29) | 0.24 (0.18, 0.30) |
| Raynaud’s | 0.06 (0.02, 0.10) | 0.07 (0.03, 0.11) |
| Finger ulcers | 0.09 (0.05, 0.13) | 0.09 (0.05, 0.13) |
| Intestinal problems | 0.07 (0.03, 0.10) | 0.06 (0.03, 0.10) |
| Breathing problems | 0.23 (0.19, 0.28) | 0.21 (0.17, 0.25) |
| Visit number | 0.025 (−0.001, 0.051) | 0.049 (0.018, 0.079) |
| Unstandardized visit no. | 0.018 (−0.001, 0.036) | 0.034 (0.013, 0.056) |
HAQ: Health Assessment Questionnaire.