Summary of distribution and anchor-based estimates of FACIT-Fatigue minimally important difference (MID).
| 1/3 SD | 1/2 SD | SEM | Anchor-based Differences and Change Scores Based on Responsiveness Analyses* | Estimated MID | |
|---|---|---|---|---|---|
| Baseline | 3.8 | 5.8 | 2.8 | 2.5, 2.6, 2.7, 3.2, 5.4, 6.1, 6.2, 7.1, 8.2, 8.4 | 3 to 7 points |
| Week 12 | 4.3 | 6.5 | 2.9 | ||
| Week 24 | 4.1 | 6.2 | 2.8 | ||
| Week 52 | 4.6 | 6.8 | 2.7 |
↵* Statistically significant differences corresponding to effect sizes between sizes between 0.20 and 0.70. FACIT: Functional Assessment of Chronic Illness Therapy; SEM: standard error of measurement.