Laboratory criteria | |
Decreased platelet count (< 26.2 × 109/l) | 27 (81.8) |
Elevated levels of aspartate aminotransferase (> 59 U/l) | 25 (75.8) |
Decreased white blood cell count (< 4.0 × 109/l) | 11 (33.3) |
Hypofibrinogenemia (< 2.5 g/l) | 9 (27.3) |
Clinical criteria | |
Central nervous system dysfunction (seizure) | 1 (3.0) |
Hemorrhages (purpura, mucosal bleeding) | 1 (3.0) |
Hepatomegaly (> 3 cm below the costal arch) | 3 (9.1) |
Histopathological criterion | |
Evidence of macrophage hemophagocytosis in the bone marrow aspirate | 3 (9.1) |