Frequency of selection of the 28 MAS features by the 232 questionnaire respondents. median and mean ranks of features, and percentage of respondents attributing high rank to each feature.
| Feature | No. (%) Respondents Who Selected the Feature | Median Rank | Mean (SD) Rank | Respondents Giving Rank 8–10 to Feature, % | Respondents Giving Rank 5–10 to Feature, % |
|---|---|---|---|---|---|
| Falling platelet count | 201 (86.6) | 6.5 | 6.1 (2.3) | 24.6 | 61.6 |
| Hyperferritinemia | 194 (83.6) | 7 | 6.5 (3.0) | 39.2 | 53.9 |
| Bone marrow hemophagocytosis | 188 (81.0) | 9 | 6.9 (3.6) | 44.8 | 55.2 |
| Increased liver enzymes | 174 (75) | 5 | 5.0 (2.4) | 13 | 40.9 |
| Falling leukocyte count | 172 (74.1) | 5 | 5.6 (2.5) | 20.3 | 46 |
| Persistent continuous fever ≥ 38°C | 158 (68.1) | 7 | 6.0 (3.4) | 30.2 | 40.1 |
| Falling erythrocyte sedimentation rate | 142 (61.2) | 6 | 5.5 (2.7) | 15.9 | 38.8 |
| Hypofibrinogenemia | 142 (61.2) | 5 | 5.4 (2.4) | 12.9 | 36.6 |
| Hypertriglyceridemia | 135 (58.2) | 5 | 5.1 (2.7) | 16.8 | 31 |
| Central nervous system dysfunction | 104 (44.8) | 5 | 5.0 (2.9) | 11.6 | 23.7 |
| Falling hemoglobin level | 100 (43.1) | 5 | 4.8 (2.3) | 4.3 | 23.3 |
| Prolongation of clothing times | 81 (34.9) | 4.5 | 4.5 (2.3) | 4.7 | 17.2 |
| Increased D-dimer | 76 (32.8) | 5 | 5 (2.6) | 7.3 | 19.4 |
| Hemorragic manifestations | 72 (31.0) | 5 | 5.3 (3.0) | 10 | 17.7 |
| Liver enlargement | 71 (30.6) | 4 | 4.8 (2.8) | 7.3 | 14.2 |
| Spleen enlargement | 57 (24.6) | 4 | 4.5 (2.8) | 4.3 | 10.3 |
| Increased lactic dehydrogenase | 45 (19.4) | 6 | 5.5 (2.6) | 4.7 | 11.6 |
| Increased soluble IL-2 receptor α | 39 (16.8) | 6 | 5.1 (3.1) | 4.7 | 9.1 |
| Increased soluble CD163 | 27 (11.6) | 5 | 5.2 (3.0) | 4.3 | 6 |
| Lymphadenopathy | 22 (9.5) | 4 | 4.4 (2.9) | 1.3 | 3.4 |
| Decreased albumin | 19 (8.2) | 3 | 4.3 (2.9) | 1.3 | 2.6 |
| Hyponatremia | 16 (6.9) | 5 | 5 (3.2) | 1.7 | 3.9 |
| Arthritis improvement | 14 (6.0) | 2 | 3.1 (2.4) | 0.9 | 0.9 |
| Renal failure | 13 (5.6) | 2.5 | 3.6 (2.9) | 0.9 | 1.7 |
| Jaundice | 9 (3.9) | 5 | 5.9 (3.3) | 1.7 | 2.2 |
| Increased bilirubin | 9 (3.9) | 2 | 3.4 (2.0) | 0 | 1.7 |
| Respiratory failure | 6 (2.6) | 3 | 4.4 (3.0) | 0.4 | 0.9 |
| Cardiac failure | 5 (2.2) | 3 | 3.8 (2.6) | 0 | 0.9 |