Table 3.

A proposed modification of the GRAPPA grid to guide treatment decisions.

Grade
DomainNever Involved (E)Inactive (D)Mild Requiring NSAID (C)Moderate Requiring DMARD (B)Active Requiring Biologics (A)
Peripheral arthritisJoint count = 0, normal function1–4 joints (swollen or tender); normal function (HAQ < 0.5)≤ 4 joints but function impaired; or > 4 joints, normal function>4 joints and function impaired
Skin diseasePASI < 1PASI 1–10 and DLQI ≤ 10PASI ≤ 10 but DLQI > 10; or PASI > 10 but DLQI ≤ 10PASI > 10 and DLQI > 10
EnthesitisLEI = 01–3 sites; normal function (HAQ < 0.5)≤ 3 sites but function impaired; or > 3 sites but normal function>3 sites and function impaired
DactylitisNo tender dactylitis1–3 digits; normal function (HAQ < 0.5)≤ 3 digits but function impaired; or > 3 digits but normal function> 3 digits and has function impaired
Spinal diseaseBASDAI < 2BASDAI 2–4; normal function (ASQoL < 6)BASDAI > 4 but normal function; BASDAI < 4 but function impairedBASDAI > 4 and function impaired
  • ASQoL: Ankylosing Spondylitis Quality of Life Questionnaire31; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index23; DLQI: Dermatology Quality of Life Index32; HAQ: Health Assessment Questionnaire33; LEI: Leeds Enthesitis Index29; PASI: Psoriasis Area and Severity Index34.