Table 2.

Single-marker association analysis of the 6 SNP in ARTS1 in 471 AS cases and 456 controls. Adjusted p values were obtained by multivariate logistic regression adjusted for age at examination and sex.

dbSNPRisk AlleleFrequency of Risk AlleleMAFpCovariate-adjusted pOR (95% CI)
CasesControlsCasesControls
rs26653G0.620.580.380.420.10410.10751.17 (0.97, 1.42)
rs27434A0.510.430.490.430.00680.00039*1.38 (1.09, 1.74)
rs27640T0.560.530.440.470.36600.31741.14 (0.86, 1.50)
rs27529G0.600.550.400.450.02930.0083*1.23 (1.02, 1.49)
rs26510T0.590.550.410.450.08720.05771.18 (0.98, 1.43)
rs27582A0.570.530.430.530.37180.46351.14 (0.86, 1.50)
  • * Significant after Bonferroni correction. SNP: single-nucleotide polymorphism; AS: ankylosing spondylitis; MAF: minor allele frequency.