Baseline demographic, biochemical, and hemodynamic characteristics of subjects with rheumatoid arthritis and controls. Values represent mean ± standard deviation.
| Characteristic | Control Group, n = 10 | Patient Group 1, n = 15 | Patient Group 2, n = 15 |
|---|---|---|---|
| Age, yrs | 58.5 ± 17.8 | 53.7 ± 15.4 | 54.8 ± 14.7 |
| No. male/female | 3/7 | 2/13 | 3/12 |
| Body mass index, kg/m2 | 25.8 ± 3.7 | 25.5 ± 3.3 | 25.8 ± 3.1 |
| IgM rheumatoid factor, +/− | 0/0 | 15/5 | 14/6 |
| ESR, mm/h | 8.10 ± 3.38 | 56.93 ± 20.81* | 58.33 ± 22.02* |
| CRP, mg/l | 3.05 ± 0.42 | 33.06 ± 14.13* | 31.46 ± 14.33* |
| TC, mg/dl | 177.20 ± 14.09 | 224.66 ± 31.12* | 228.13 ± 11.75* |
| TG, mg/dl | 91.30 ± 19.80 | 137.33 ± 47.31* | 126.93 ± 31.97** |
| LDL-C, mg/dl | 124 ± 16.46 | 142.33 ± 24.41** | 142.66 ± 24.33** |
| HDL-C, mg/dl | 54.50 ± 11.81 | 44.06 ± 9.12** | 41.60 ± 10.85* |
| TC/HDL-C | 3.4 ± 0.27 | 5.31 ± 1.38* | 5.75 ± 1.44* |
| LDL-C/HDL-C | 2.49 ± 0.81 | 3.40 ± 1.03* | 3.56 ± 0.82* |
| MDA, nmol/ml | 2.05 ± 0.45 | 4.35 ± 0.75* | 4.42 ± 0.81* |
| Resistin, ng/ml | 6.86 ± 1.31 | 9.17 ± 1.53* | 9.37 ± 1.80* |
| Adiponectin, μg/ml | 12.27 ± 1.83 | 19.81 ± 1.95* | 19.21 ± 2.10* |
| TNF-α, pg/ml | 3.71 ± 0.97 | 9.79 ± 3.42* | 10.13 ± 2.90* |
| FMD, % | 7.93 ± 2.31 | 3.93 ± 1.29* | 3.72 ± 2.02* |
Significance was determined using one-way analysis of variance for independent samples (ANOVA).
↵* p < 0.001;
↵** p < 0.05 compared to controls. ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; TC: total cholesterol; TG: triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; MDA: serum malondialdehyde; TNF-α: tumor necrosis factor-α; FMD: flow-mediated dilation.