Associations of anti-ß2 glycoprotein I (anti-ß2-GPI), by isotype, in systemic lupus erythematosus.
| Factor | IgA Anti-ß2-GPI Positive, % | IgA Anti-ß2-GPI Negative, % | p for IgA Anti-ß2-GPI | OR for IgA Anti-ß2-GPI (95% CI) | OR for IgG Anti-ß2-GPI (95% CI) | OR for IgM Anti-ß2-GPI (95% CI) |
|---|---|---|---|---|---|---|
| Transient ischemic attack | 5.7 | 2.6 | 0.070 | 2.30 (1.00–5.31) | 3.69 (1.21–11.3) | 2.64 (1.11–6.27) |
| Superficial thrombophlebitis | 4.4 | 3.7 | 0.647 | 1.20 (0.51–2.85) | 3.78 (1.37–10.4) | 1.99 (0.86–4.57) |
| Deep venous thrombosis | 19.9 | 10.7 | 0.003 | 2.08 (1.31–3.30) | 3.33 (1.67–6.62) | 0.94 (0.52–1.69) |
| Other venous thrombosis | 4.4 | 4.2 | 0.827 | 1.06 (0.45–2.49) | 3.36 (1.23–9.17) | 1.18 (0.48–2.92) |
| Stroke | 11.9 | 7 | 0.050 | 1.79 (1.01–3.15) | 2.39 (1.02–5.61) | 1.27 (0.66–2.46) |
| Myocardial infarction | 1.2 | 2.9 | 0.397 | 0.43 (0.10–1.87) | 0.91 (0.12–6.95) | 0.27 (0.04–2.06) |
| Total arterial thrombosis (TIA, stroke, MI, and digital gangrene) | 17.2 | 12.5 | 0.083 | 1.44 (0.9–2.34) | 2.18 (1.04–4.60) | 1.42 (0.84–2.39) |
| Total venous thrombosis (superficial, DVT, and other venous) | 24.2 | 15.79 | 0.0097 | 1.70 (1.12–2.59) | 3.03 (1.58–5.79) | 1.22 (0.75–1.97) |
TIA: transient ischemic attack; MI: myocardial infarction; DVT: deep venous thrombosis.