Table 1.

Pimonidazole and GLUT-1 staining in epidermis. Results are median (range). 0 = no staining; 1 = low staining, 2 = medium staining, 3 = high staining.

Granular LayerPrickle LayerBasal Layer
Pimonidazole
  SSc forearm (n = 9)3.0 (2.0–3.0)1.0 (0.5–2.0)1.0 (0.0–2.5)
  SSc buttock (n = 9)3.0 (2.0–3.0)1.5 (1.0–2.5)1.0 (0.0–1.0)
GLUT-1
  SSc forearm (n = 9)0.0 (0.0–0.5)2.0 (1.8–3.0)2.0 (1.0–3.0)
  SSc buttock (n = 9)0.0 (0.0–0.0)2.5 (1.8–3.0)2.5 (1.5–3.0)
  Healthy control forearm (n = 12)0.0 (0.0–0.0)1.6 (0.5–2.5)1.6 (0.5–2.5)