Relative risk of RA by history of periodontal surgery and teeth lost among women in the Nurses’ Health Study, 1992–2004 (n = 81,132).
| Factor | Cases, n | Person-yrs | Age-adjusted RR (95% CI) | Multivariate RR (95% CI)* |
|---|---|---|---|---|
| Periodontal surgery | ||||
| No | 264 | 829,194 | 1.0 (ref) | 1.0 (ref) |
| Yes | 28 | 68,876 | 1.27 (0.86, 1.88) | 1.24 (0.83, 1.83) |
| p | 0.23 | 0.29 | ||
| Teeth lost | ||||
| None | 243 | 758,614 | 1.0 (ref) | 1.0 (ref) |
| 1–4 | 44 | 125,686 | 1.09 (0.79–1.50) | 1.02 (0.74, 1.43) |
| 5 or more | 5 | 13,769 | 1.13 (0.46, 2.74) | 1.18 (0.47, 2.95) |
| p for trend | 0.58 | 0.76 | ||
↵* Adjusted for number of natural teeth, alcohol intake, pack-years of smoking, body mass index, father’s occupation, age at menarche, postmenopausal status and hormone use, parity and duration of breastfeeding, and regularity of menses.