Table 1.

Remissions in observational studies * remission over 6 months at any point. Results are mean values unless denoted “i” indicating median data; “ii”, DAS.

Study	Year	Remission	Disease Duration, mo	Age, yrs	Female, %	RF+, %	ESR	DAS28	Followup, mo	DMARD	Number at Entry	Number at Followup	Remission, at Study End (%)
Prevoo⁹	1996	ACR	< 12	55ⁱ	63	78	—	—	72	Monotherapy	227	49	15 (31)
Eberhardt³⁸	1998	ACR	< 24	—	63	75	29	—	60	Monotherapy	183	176	37 (20)**
Young³⁹	2000	ACR	8	—	66	63	—	—	60	Monotherapy	941	732	94 (13)
Makinen⁴⁰	2005	ACR	5	56	61	54	—	—	60	Monotherapy	127	111	19 (17)
Möttönen⁴¹	1996	ACR	< 24	46	75	63	30ⁱ	—	72	Combination included	142	142	45 (32)
Lindqvist⁴²	2002	ACR	< 24	—	63	75	—	—	120	Combination included	183	163	30 (18)
Sanmarti⁴³	2003	ACR	< 24	52	78	—	45	5.8	12	Combination included	65	60	12 (20)
Fransen³⁰	2004	ACR	< 12	55	66	76	—	—	72	Combination included	424	77	9 (12)
Cantagrel¹⁷	1999	DAS	< 12	—	—	71	—	—	24	Not stated	108	108	15 (14)
Tengstrand⁴⁴	2004	DAS	< 12	57	64	58	—	5.1	24	Monotherapy	844	844	279 (33)
Vázquez⁴⁵	2007	DAS	< 24	55	81	74	40	5.7	24	Monotherapy	115	105	34 (32)
Khanna⁴⁶	2007	DAS	< 14	51	—	100	43	5.5	24	Monotherapy	200	101	33 (33)
Gossec⁴⁷	2004	DAS	< 12	51	73	81	40	4.1ⁱⁱ	60	Combination included	191	165	38 (23)
Forslind⁴⁸	2007	DAS	≤ 12	58	64	60	—	5.3	60	Combination included	698	608	234 (39)
Proudman²³	2007	DAS	< 24	56	76	61	42	5.3	36	Combination included	61	52	28 (54)
Sanmarti⁴⁹	2007	DAS	< 24	55	81	74	40	5.7	24	Combination included	115	105	34 (32)
Machold²¹	2007	DAS	≤ 3	51	75	—	—	—	36	Combination included	138	55	16 (29)