KLK1 polymorphisms in LN patients and healthy controls in Han Chinese. Values are number (%).
| SNP | Patients, n = 306 | Controls, n = 338 | p |
|---|---|---|---|
| rs2740502 | |||
| Genotype frequency | |||
| G/G | 13 (4.2) | 20 (5.9) | 0.246 |
| C/G | 119 (38.9) | 112 (33.1) | |
| C/C | 174 (56.9) | 206 (60.9) | |
| Allele frequency | |||
| G (vs C) | 145 (23.7) | 152 (22.5) | 0.607 |
| Recessive model | |||
| G/G (vs C/G + C/C) | 13 (4.2) | 20 (5.9) | 0.337 |
| Dominant model | |||
| G/G + C/G (vs C/C) | 132 (43.1) | 132 (39.1) | 0.293 |
| rs5516 | |||
| Genotype frequency | |||
| G/G | 13 (4.2) | 8 (2.4) | 0.373 |
| C/G | 94 (30.7) | 111 (32.8) | |
| C/C | 199 (65.0) | 219 (64.8) | |
| Allele frequency | |||
| G (vs C) | 120 (19.6) | 127 (18.8) | 0.709 |
| Recessive model | |||
| G/G (vs C/G + C/C) | 13 (4.2) | 8 (2.4) | 0.179 |
| Dominant model | |||
| G/G + C/G (vs C/C) | 107 (35.0) | 119 (35.2) | 0.949 |
| rs5517 | |||
| Genotype frequency | |||
| T/T | 54 (17.6) | 57 (16.9) | 0.471 |
| C/T | 159 (52.0) | 163 (48.2) | |
| C/C | 93 (30.4) | 118 (34.9) | |
| Allele frequency | |||
| T (vs C) | 267 (43.6) | 277 (41.0) | 0.336 |
| Recessive model | |||
| T/T (vs C/T + C/C) | 54 (17.6) | 57 (16.9) | 0.793 |
| Dominant model | |||
| T/T + C/T (vs C/C) | 213 (69.6) | 220 (65.1) | 0.222 |
p values were calculated by chi-square analysis using 2 × 3 (comparison of genotype frequencies) or 2 × 2 (other comparisons) contingency tables.