Weighted multivariable adjusted final models for radiographic OA in the left/right knee/hip (OR with 95% CI), with contralateral joint data by race/ethnicity. OR are multivariable-adjusted and derived from models that included all the variables in a column: age, sex, race/ethnicity, BMI, contralateral Kellgren-Lawrence (KL) grade, and other joint site maximum KL grade.
| 4 Models (by outcome variable) | ||||
|---|---|---|---|---|
| Explanatory Variable | Left Knee Model OR (95% CI) | Right Knee Model OR (95% CI) | Left Hip Model OR (95% CI) | Right Hip Model OR (95% CI) |
| Among Whites | ||||
| Contralateral KL grade (for outcome KL grade ≥ 2*) | ||||
| 2 vs 0/1 | 10.2 (7.4, 14.0) | 12.9 (9.8, 17.1) | 9.4 (7.3, 12.2) | 9.2 (7.1, 11.9) |
| 3/4 vs 0/1 | 47.3 (27.0, 82.8) | 36.5 (19.9, 67.2) | 89.7 (33.6, 239.3) | 225.0 (83.6, 605.7) |
| Contralateral KL grade (for outcome KL grade ≥ 3**) | Same as for outcome KL grade ≥ 2 (above) (odds were proportional) | Same as for outcome KL grade ≥ 2 (above) (odds were proportional) | ||
| 2 vs 0/1 | 5.3 (2.7, 10.6) | 9.6 (5.7, 16.1) | ||
| 3/4 vs 0/1 | 83.3 (40.7, 170.5) | 104.2 (57.5, 188.7) | ||
| Among African Americans | ||||
| Contralateral KL grade (for outcome KL grade ≥ 2*) | Same As Whites outcome KL grade ≥ 2 (no race/ethnicity interaction) | Same as Whites outcome KL grade ≥ 2 (no race/ethnicity interaction) | Same as Whites outcome KL grade ≥ 2 (no race/ethnicity interaction) | |
| 2 vs 0/1 | 24.0 (14.0, 41.1) | |||
| 3/4 vs 0/1 | 64.1 (32.0, 128.4) | |||
| Contralateral KL grade (for outcome KL grade ≥ 3**) | Same as Whites outcome KL grade ≥ 3 (no race/ethnicity interaction) | Same as Whites outcomeKL grade ≥ 3 (no race/ethnicity interaction) | Same as Whites outcome KL grade ≥ 3 (no race/ethnicity interaction) | |
| 2 vs 0/1 | 12.5 (5.7, 27.2) | |||
| 3/4 vs 0/1 | 112.8 (52.0, 244.8) | |||
| Overall | ||||
| Other joint site maximum KL grade*** | ||||
| 2 vs 0/1 | 1.5 (1.2, 2.0) | 1.4 (1.0, 1.8) | 1.5 (1.2, 2.0) | 1.5 (1.1, 2.0) |
| 3/4 vs 0/1 | 1.7 (0.9, 3.0) | 1.8 (1.0, 3.3) | 1.8 (1.2, 2.7) | 1.6 (1.0, 2.4) |