Relationship between arterial stiffness (augmentation index, AIX@75) and 5 health status measures in 114 patients with rheumatoid arthritis without overt arterial disease. EQ-5D score has been multiplied by 100 to make it more easily comparable with overall-arthritis and overall-health scores. Arterial stiffness (augmentation index standardized to a heart rate of 75 bpm, AIX@75) is the dependent variable. Relationship reported between AIX@75 and health status measures has been adjusted for 10 variables (age, sex, pack-years of smoking, fasting total cholesterol, mean arterial blood pressure, Godin physical activity score, daily fruit and vegetables, study ESR, arthritis duration, ACR RA criteria) using multiple linear regression.
| Measure | Regression Coefficients | Summary of Regression Models | ||||
|---|---|---|---|---|---|---|
| Regression Coefficient (B) | 95% CI | p | Multiple Correlation Coefficient (R) | Adjusted R2 | p (ANOVA) | |
| Stanford HAQ | 2.76 | 1.11 to 4.40 | 0.001 | 0.73 | 0.48 | < 0.0001 |
| Damaged joint count | 0.17 | 0.04 to 0.29 | 0.009 | 0.72 | 0.46 | < 0.0001 |
| Arthritis overall | −0.08 | −0.14 to −0.02 | 0.008 | 0.72 | 0.46 | < 0.0001 |
| Health overall | −0.08 | −0.17 to 0.00 | 0.05 | 0.71 | 0.45 | < 0.0001 |
| EQ-5D | −0.04 | −0.09 to 0.01 | 0.16 | 0.70 | 0.44 | < 0.0001 |
EQ-5D: health questionnaire with 5 dimensions; ESR: erythrocyte sedimentation rate; ACR: American College of Rheumatology; RA: rheumatoid arthritis; HAQ: Health Assessment Questionnaire.