Table 2.

Proportion of patients (%) with immunoglobulin (Ig) levels below laboratory lower limit of normal (LLN) by retreatment group. Normal ranges for IgG, IgM, and IgA are 6.72–14.4, 0.57–2.85, and 0.59–3.96 mg/ml, respectively.

Percentage of Patients with Immunoglobulin < LLN
Week 24 (prerandomization)Week 48 (primary endpoint)
IgG
  Placebo retreatment54
  Rituximab retreatment77
IgM
  Placebo retreatment914
  Rituximab retreatment1426
IgA
  Placebo retreatment00
  Rituximab retreatment0.30.4