Table 4A.

Comparison of glucose metabolism by HCQ and disease status among women not using prednisone, by mean value adjusted for age, disease duration, waist circumference, prednisone dose, CRP, menopausal status, and NSAID; plus (a) immunosuppressants and SLEDAI for women with SLE, or (b) nonbiologic DMARD (excluding HCQ) and TNF inhibitors for women with RA.

Metabolism Factors+ HCQ− HCQp
Fasting glucose, mg/dl
  Women with SLE, n = 9283.589.10.01
  Women with RA, n = 10387.090.30.30
logInsulin
  Women with SLE2.532.540.93
  Women with RA2.452.260.15
logHOMA-B
  Women with SLE5.475.240.08
  Women with RA5.254.940.09
logHOMA-IR
  Women with SLE0.941.020.54
  Women with RA0.910.750.27
  • HCQ: hydroxychloroquine; SLE: systemic lupus erythematosus; RA: rheumatoid arthritis; HOMA-B: homeostasis model assessment - ß cell; HOMA-IR: homeostasis model assessment-insulin; CRP: C-reactive protein; NSAID: nonsteroidal antiinflammatory drug; SLEDAI: Systemic Lupus Erythematosus Disease Activity Index; DMARD: disease-modifying antirheumatic drug; TNF: tumor necrosis factor.